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Case Reports IDCases. 2025 May 10:40:e02259. doi: 10.1016/j.idcr.2025.e02259 Q41.02025

Diagnosis of cystoisosporiasis in a patient with HIV and modestly decreased CD4 counts

CD4细胞计数轻度降低的HIV患者卡氏等孢子虫病的诊断 翻译改进

Kevin Kurator  1, Leona Mason  2, David Bruckner  3, Hongying Tan  4, Glenn Mathisen  2

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作者单位

  • 1 Olive View-UCLA Medical Center, Department of Medicine, United States.
  • 2 Olive View-UCLA Medical Center, Department of Infectious Diseases, United States.
  • 3 UCLA, Department of Pathology, United States.
  • 4 Olive View-UCLA Medical Center, Department of Pathology, United States.
  • DOI: 10.1016/j.idcr.2025.e02259 PMID: 40511254

    摘要 中英对照阅读

    Cystoisosporiasis is caused by a coccidian parasite that is found worldwide and can cause diarrheal illness. It is more common in the immunocompromised, in whom it can cause extended and severe disease courses. Diagnosis is not always straightforward as oocytes are not always present in routine stool samples, but it is possible to visualize the organism with specialized staining techniques as well as within enterocytes on intestinal biopsies. We present a case in which this mode of diagnosis was crucial for determining the cause of diarrhea in a patient with HIV and CD4 count above 200 cells/mm3.

    Keywords: Biopsy; Cystoisospora; HIV; Stool ova & parasites.

    Keywords:cystoisosporiasis; hiv patients; cd4 counts

    囊异孢子虫病是由一种在全球范围内发现的球虫寄生虫引起,可导致腹泻疾病。这种病症在免疫功能低下的人群中更为常见,在这些人当中它可能导致长期且严重的病情发展。由于卵囊并不总是出现在常规粪便样本中,因此诊断并非总是一目了然,但是可以通过专门的染色技术以及肠黏膜活检标本中的上皮细胞来观察到该病原体。我们报告了一例在一名HIV患者(CD4计数高于200个细胞/ mm³)中通过这种方式确诊腹泻病因的情况。

    关键词:活检;囊异孢子虫;HIV;粪便卵和寄生虫检查

    关键词:囊状等孢球虫病; 艾滋病患者; CD4细胞计数

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    期刊名:Idcases

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    ISSN:2214-2509

    e-ISSN:2214-2509

    IF/分区:1.0/Q4

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    Diagnosis of cystoisosporiasis in a patient with HIV and modestly decreased CD4 counts