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Frequent Vocalizations and DBS-Responsive Hyperkinesia in a Striatal Disinhibition Rat Model for Tourette Syndrome

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Background: The lack of a rodent model for both motor and phonic tics hinders research on deep brain stimulation (DBS) for refractory Tourette syndrome (TS). Striatal disinhibition with a GABA-A antagonist (bicuculline) was previ... ...