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PloS one. 2025 Jun 12;20(6):e0325002. doi: 10.1371/journal.pone.0325002 Q22.62025

Time to first antenatal care contact and pooled prevalence among reproductive-age women in East Africa: Log-logistic shared frailty model

东非地区育龄妇女首次产前护理联系时间及患病率:Log-Logistics共享脆弱性模型 翻译改进

Simachew Getaneh Endalamew  1, Fetlework Gubena Arage  2, Asefa Adimasu Taddese  2, Dejen Kahsay Asgedom  3, Bewuketu Terefe  4, Solomon Keflie Assefa  2

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作者单位

  • 1 Department of Veterinary Epidemiology and Public Health, School of Veterinary Medicine, Bahir Dar University, Bahir Dar, Ethiopia.
  • 2 Department of Biostatistics and Epidemiology, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
  • 3 Department of Public Health, College of Medicine and Health Science, Samara University, Samara, Ethiopia.
  • 4 Department of Community Health Nursing, School of Nursing, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
  • DOI: 10.1371/journal.pone.0325002 PMID: 40504855

    摘要 中英对照阅读

    Background: Antenatal care (ANC), the provision of prenatal healthcare by skilled medical practitioners, is essential for ensuring the well-being of pregnant women and their fetuses. It reduces maternal and child morbidity and mortality. However, there is a lack of comprehensive, region-wide analyses of ANC initiation, particularly across diverse East African countries. Therefore, this study aimed to determine the time to first antenatal care and its associated factors in East African countries.

    Methods: Demographic and Health Survey (DHS) data from 2012-2022 consisting of 12 countries were extracted. A total of 93,213 weighted reproductive-age women (15-49 years) were included in this study. A Kaplan-Meier survivor curve was generated to estimate the time of the first antenatal care contact. A log-rank test was used to compare the difference in survival curves. The log-logistic gamma shared frailty model was selected based on the reduced Akaike and Bayesian Information Criteria, and Cox-Snell residual plot. The shared frailty model was utilized to capture the correlation of outcomes within clusters (countries), as individuals within the same country may experience similar risks.

    Results: The pooled prevalence of women with a minimum of 4 ANC contacts in East African countries was 57.7% (95% CI: (49.9-65.1%). The variability in effect sizes of ANC utilization across included countries is estimated at [Formula: see text] 0.2032 [95% CI: 0.1111-0.6611]. The overall median time to the first antenatal care contact was 4 months. The log-logistic shared frailty model showed that place of residence [ϕ = 1.014, 95% CI: (1.006, 1.021)], maternal age [ϕ = 0.978, 95% CI: (0.970, 0.980)], women's education level [ϕ = 0.964, 95% CI: (0.952, 0.971)], marital status [ϕ = 0.970, 95% CI: (0.963, 0.978)], wealth index [ϕ = 0.990, 95% CI: (0.982, 0.997)], healthcare distance [ϕ = 0.975, 95% CI: (0.969, 0.980)], and parity [ϕ = 1.111, 95% CI: (1.093, 1.129)] were significant determinants of time at first antenatal care visit.

    Conclusion: Women in East Africa initiated their first ANC visit later than the optimal period recommended by the World Health Organization (WHO). The positive correlation between early ANC initiation and access to media, healthcare access, and educational attainment may be utilized to promote increased early engagement in ANC services. Thus, governments and other responsible bodies should strive to implement programs to enhance access to healthcare and education, particularly for women living in rural areas, to improve the early initiation of antenatal care visits.

    Keywords:time to first antenatal care; reproductive-age women; east africa

    背景: 产前保健(ANC),由熟练的医疗从业人员提供的孕期医疗服务,对于确保孕妇及其胎儿的健康至关重要。它可以减少孕产妇和儿童发病率及死亡率。然而,在多样化的东非国家中缺乏全面、区域性的早期产前护理分析。因此,本研究旨在确定东非各国首次产前检查的时间及其相关因素。

    方法: 从2012年至2022年的Demographic and Health Survey (DHS) 数据中提取了12个国家的数据,总共纳入93,213名加权后的育龄女性(15-49岁)。使用Kaplan-Meier生存曲线来估计首次产前检查的时间。采用log-rank检验比较不同生存曲线之间的差异。基于减少的Akaike和Bayesian信息准则及Cox-Snell残差图,选择了对数逻辑伽马共享脆弱性模型。该共享脆弱性模型用于捕捉国家内集群(国家)内部结果的相关性,因为同一个国家内的个体可能会经历相似的风险。

    结果: 在东非各国中,至少有4次产前检查的女性合并患病率为57.7% (95% CI: 49.9-65.1%)。所纳入国家之间产前护理利用率效应量变化估计为[公式:见文本] 0.2032 [95% CI: 0.1111-0.6611]。总体而言,首次产前检查的中位时间是4个月。对数逻辑共享脆弱性模型显示居住地、母亲年龄、女性受教育程度、婚姻状况、财富指数、医疗服务距离和生育次数均为首次产前访问时间的重要决定因素。

    结论: 东非的妇女比世界卫生组织(WHO)推荐的最佳时期更晚开始第一次产前检查。早期产前护理启动与媒体接触、医疗保健获取及教育程度之间的正相关关系可用于促进早期参与产前服务。因此,政府和其他责任机构应努力实施计划以提高医疗和教育资源的可获得性,特别是针对居住在农村地区的女性,从而改善首次产前访问的早期开始。

    关键词:初次产前检查时间; 生育年龄妇女; 东非

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    ISSN:1932-6203

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