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Thiram-driven XBP1 and CHOP pathways orchestrate ER stress and avian tibial dyschondroplasia via metabolic inflammatory axis

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Thiram, one of the most widely used dithiocarbamate fungicides, has turned out to be a very potent cellular metabolic homeostasis disruptor through the induction of endoplasmic reticulum (ER) stress. The present study examines the mechanistic foundation of thi... ...