Folliculin deletion in the mouse kidney results in cystogenesis of the loops of Henle via aberrant TFEB activation
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The mammalian kidney contains numerous nephrons connected to the collecting ducts, and each nephron consists of a glomerulus, a proximal tubule, the loop of Henle (LoH), and a distal tubule. Folliculin (FLCN) is a causative gene for Birt-Hogg-Dubé (BHD) syndr... ...
