Objective: This study aimed to evaluate the effectiveness of various alloplastic facial implants in correcting facial defects based on post-operative complications and failure rates in patients who underwent facial skeletal augmentation.

Method: A comprehensive search for articles reporting relevant articles was using Google Scholar and PubMed databases. Data from publications that satisfied the predefined inclusion criteria were synthesized and analyzed using OpenMeta [Analyst] software.

Results: A total of 48 studies with a population size of 3701 patients who received 4139 alloplastic facial implants were included in this analysis. The complication rate was 10.7% (95% confidence intervals [CI] [8.3%, 13.2%], and I² =89.35%). Paranasal implants had the highest rate of complications of 15.1% (95% CI [7.8%, 22.3%], and malar implants had the lowest complication rate of 7.4% (95% CI 3.8%, 11.1%]) I² = 72.62%). In 15 studies that had malar implants, 853/1788 (45.8%) of the patients received malar implants (95% CI [0.356, 0.561]). In 8 studies that included mandibular implants, 265 (56%) of 508 patients received mandibular implants (95% CI [0.474, 0.645]); in 11 studies, 371/489 (76.1%) received nasal or paranasal implants (95% CI of [0.565, 0.912]), while in 3 studies, 14/15 (85.5%) received frontal implant (95% CI of [0.645, 0.997]). In 17 studies that investigated the use of chin implants, 1366/1366 (100%) of the eligible patients received chin implants (95% CI [0.995, 1.000], I² = 0%). The complication rate was 2.78% for silicone, 1.02% for calcium hydroxyapatite, and 2.48 for Medpor.

Conclusion: Alloplastic facial implants are a viable alternative to enhancing facial beauty and performing facial skeletal augmentation with a relatively lower risk of complications associated with all facial implants.

Keywords: Aesthetic Surgery; Alloplastic Facial Implants; Facial Beauty; Skeletal Augmentation.

Crown Copyright © 2025. Published by Elsevier Ltd. All rights reserved.

目标: 本研究旨在评估各种异体面部植入物在纠正面部缺陷方面的有效性，基于术后并发症和失败率对接受面部骨骼增强手术的患者进行评价。

方法: 使用Google Scholar和PubMed数据库进行了全面的文章搜索以找到相关文献。符合预定义纳入标准的出版物数据被汇总并利用OpenMeta [Analyst]软件进行了分析。

结果: 本分析共包括48项研究，涉及3701名接受4139种异体面部植入物手术的患者。并发症的发生率为10.7%（95%置信区间[CI] [8.3%，13.2%]），I² = 89.35%）。鼻旁植入物具有最高的并发症发生率，为15.1%（95% CI [7.8%，22.3%]），颧骨植入物则有最低的并发症发生率，为7.4%（95% CI 3.8%，11.1%]) I² = 72.62%）。在包含颧骨植入物的15项研究中，共1788名患者中有853人接受了该手术（占比45.8%，95% CI [0.356, 0.561]）；在包括下颌植入物的8项研究中，共有508名患者中的265人进行了该项手术（占比56%，95% CI [0.474, 0.645]）。而在包含鼻部或鼻旁植入物的11项研究中，489名患者中有371人接受了该手术（占比76.1%，95% CI [0.565, 0.912]），而接受额部植入物的3项研究则有15名患者中的14人进行了该项手术（占比85.5%，95% CI [0.645, 0.997]）。在调查下巴植入物使用的17项研究中，所有符合条件的1366名患者均接受了该植入物（发生率为2.78%，95% CI [0.995, 1.000], I² = 0%）。硅胶、羟基磷灰石和Medpor的并发症发生率分别为2.78%、1.02% 和2.48%。

结论: 异体面部植入物是一种增强面部美观性和进行面部骨骼增强的有效替代方案，所有类型的面部植入物相关的并发症风险相对较低。

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