Background: Celiac disease (CD) is an autoimmune disease triggered by the ingestion of gluten in genetically predisposed individuals. It is more commonly diagnosed in children presenting typical clinical signs and symptoms but most of the CD patients diagnosed in the developed world are silent cases with no prominent gastrointestinal features. Thus, there are silent forms of the disease in which oral manifestations are the first sign. In the pediatric population oral health can affect growth and self-esteem and have a negative impact in their life quality.

Aim: To assess the prevalence and types of oral manifestations in pediatric patients with CD.

Methods: We performed a comprehensive literature search in PubMed, Scielo, Cochrane Library and Lilacs databases from 2014-2024. Three independent researchers screened and extracted the information, applying the eligibility criteria and bias was assessed using Joanna Briggs Institute tools.

Results: Of the initial 241 articles, 14 studies fulfilled the proposed objectives and were included in the review. The main oral manifestations found were recurrent aphthous stomatitis and enamel defects. Additionally, delayed tooth eruption, angular cheilitis, glossodynia and xerostomia were also reported.

Conclusion: Assessing oral manifestations is crucial, especially in underdiagnosed cases of children with CD. Recognizing these signs helps pediatricians or general practitioners identify them during routine exams, enabling early diagnosis and treatment to prevent negative impacts on the child's and family's quality of life.

Keywords: Celiac disease; Enamel defects; Oral aphthous; Oral manifestations; Pediatric dentistry.

©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.

背景：背景:

乳糜泻（CD）是一种由遗传易感个体摄入麸质触发的自身免疫性疾病。它更常在出现典型临床症状和体征的儿童中诊断出来，但在发达国家被诊断出来的大多数乳糜泻患者是没有明显胃肠道特征的隐匿型病例。因此，存在一些疾病隐匿的形式，在这些形式中，口腔表现是第一个显现的症状。在儿科人群中，口腔健康会影响生长发育和自我价值感，并对他们的生活质量产生负面影响。

目的：

评估乳糜泻患儿口腔表现的流行率及其类型。

方法：

我们在PubMed、Scielo、Cochrane Library 和 Lilacs 数据库中进行了全面的文献搜索，时间范围为2014-2024年。三位独立的研究人员筛选和提取了符合纳入标准的信息，并使用Joanna Briggs Institute 工具评估偏倚。

结果：

在最初的241篇文章中，有14项研究达到了设定的目标并被纳入综述。主要发现的口腔表现包括复发性口疮性口炎和釉质缺陷。此外，延迟牙齿萌出、唇角炎、舌痛和口干症也被报告。

结论：

评估口腔表现至关重要，尤其是在乳糜泻儿童诊断不足的情况下。识别这些症状有助于儿科医生或全科医生在常规检查中发现它们，从而实现早期诊断和治疗，防止对患儿及其家庭的生活质量产生负面影响。

关键词：

乳糜泻；釉质缺陷；口腔口疮；口腔表现；儿童牙科学。