Dexmedetomidine improves septic acute kidney injury by inhibiting inflammation and oxidative stress through the activation of the Pink1/Park2 autophagy pathway
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Impaired autophagy is a key factor in the development of septic acute kidney injury (SAKI). Dexmedetomidine-an α2 adrenergic agonist widely used as a sedative-exerts protective effects in SAKI. However, its correlation with autophagy remains unclear. Conseque... ...
