Discovery of a novel MARK4 antagonist from safflower to improve ischemic stroke by inhibiting microglial NLRP3 inflammasome activation
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Background: Neuroinflammation has been proven to be a significant factor linked to stroke, with NLRP3 inflammasome activation being a common neuroinflammatory manifestation. Microtubule affinity regulated kinase 4 (MARK4) plays a... ...
