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Review Current microbiology. 2025 Jun 7;82(7):328. doi: 10.1007/s00284-025-04306-x Q32.62025

Targeting Metastasis: Exploring the Impact of Microbial Infections on Cancer Progression Through Innovative Biological Models

靶向转移:通过创新生物学模型探索微生物感染对癌症进展的影响 翻译改进

Mohamed A El-Tayeb  1

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  • 1 Department of Botany and Microbiology, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia. mali5@ksu.edu.sa.
  • DOI: 10.1007/s00284-025-04306-x PMID: 40481883

    摘要 中英对照阅读

    Infectious diseases, particularly viral infections, pose a significant threat to human health by contributing to cancer progression and metastasis. This review presents a novel perspective on how advanced biological models such as organoids, organ-on-a-chip systems, spheroids, and 3D bioprinting bridge critical translational gaps in research. These models replicate human physiological processes, allowing for the investigation of molecular mechanisms and th... ...点击完成人机验证后继续浏览

    感染性疾病,尤其是病毒感染,通过促进癌症进展和转移对人类健康构成重大威胁。本文综述提出了一个新颖的观点,探讨了先进的生物模型(如类器官、芯片上的器官系统、球体及3D生物打印)如何填补研究中的关键转化差距。这些模型能够复制人体生理过程,从而允许研究人员探究分子机制并评估新型疗法。本综述将探讨目前用于研究与转移相关的病毒感染的先进生物模型的状态,以更好地理解病毒诱导的变化如何影响肿瘤行为,并为未来的治疗策略提供启示。

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    期刊名:Current microbiology

    缩写:CURR MICROBIOL

    ISSN:0343-8651

    e-ISSN:1432-0991

    IF/分区:2.6/Q3

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    Targeting Metastasis: Exploring the Impact of Microbial Infections on Cancer Progression Through Innovative Biological Models