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Current microbiology. 2025 Jun 7;82(7):327. doi: 10.1007/s00284-025-04303-0 Q32.62025

Differential Microbial Composition and Fiber Degradation in Two Sloth Species (Bradypus variegatus and Choloepus hoffmanni)

两种树懒(Bradypus variegatus和Choloepus hoffmanni)的微生物组成及纤维降解的差异性研究 翻译改进

Priscila Chaverri  1, Efraín Escudero-Leyva  2  3, Darling Mora-Rojas  3, Andrea Calvo-Obando  3, Mariana González  4  5, Esteban Escalante-Campos  3  5, Esteve Mesén-Porras  3, Daniela Wicki-Emmenegger  3, Diego Rojas-Gätjens  3, Judith Avey-Arroyo  4, Mariana Campos-Hernández  3, Erick Castellón  5, Andrés Moreira-Soto  6  7, Jan Felix Drexler  6  8, Max Chavarría  2  3  5

作者单位 +展开

作者单位

  • 1 Department of Natural Sciences, Bowie State University, Bowie, MD, USA. pchaverri@bowiestate.edu.
  • 2 Centro de Investigaciones en Productos Naturales (CIPRONA), Universidad de Costa Rica, San José, Costa Rica.
  • 3 Centro Nacional de Innovaciones Biotecnológicas (CENIBiot), CeNAT-CONARE, San José, Costa Rica.
  • 4 The Sloth Sanctuary of Costa Rica, Limón, Costa Rica.
  • 5 Escuela de Química, Universidad de Costa Rica, San José, Costa Rica.
  • 6 Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt Universität Zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • 7 Tropical Disease Research Program, School of Veterinary Medicine, Universidad Nacional, Heredia, Costa Rica.
  • 8 German Centre for Infection Research (DZIF), Associated Partner Site Charité, Berlin, Germany.
  • DOI: 10.1007/s00284-025-04303-0 PMID: 40481853

    摘要 中英对照阅读

    Sloths have the slowest digestion among mammals, requiring 5-20 times longer to digest food than other herbivores, which suggests differences in their gut microbiota, particularly in plant-fiber-degrading microorganisms. Bradypus variegatus has a lower metabolic rate and moves less than Choloepus hoffmanni. However, no comprehensive studies have compared the microbiota (e.g., fungi) of these species. We hypothesized that differences in digestion and metabo... ...点击完成人机验证后继续浏览

    树懒的消化速度是哺乳动物中最慢的,其消化食物的时间比其他草食动物长5到20倍,这表明它们肠道微生物群在降解植物纤维方面存在差异。Bradypus variegatus 的代谢率较低且活动较少于Choloepus hoffmanni。然而,目前还没有全面的研究比较这两个物种的微生物群(如真菌)。我们假设这两种树懒之间的消化和代谢差异会在其微生物群组成及功能上有所体现,并使用元基因组学、分子条形码技术和纤维素降解实验对其进行了表征。结果揭示了微生物群组成的显著差异及其功能方面的不同。两种树懒都主要由细菌构成;真菌仅占0.06%-0.5%的元基因组读数。Neocallimastigomycota是一种参与其他草食动物纤维分解的厌氧真菌,在这两种树懒中含量较低,尤其是在B. variegatus中。细菌群落显示出细微差异:C. hoffmanni主要由Bacillota和Bacteroidota构成,而B. variegatus则表现出较高的Actinomycetota水平。预期的草食动物相关细菌种类(如Fibrobacter和Prevotella)相对较少见。功能分析显示降解多糖所需的碳水化合物活性酶含量较低。纤维素降解实验确认树懒仅消化摄入植物物质的大约3%-30%。这项研究揭示了肠道微生物群、代谢及消化之间可能存在互为影响的联系。

    © 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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    期刊名:Current microbiology

    缩写:CURR MICROBIOL

    ISSN:0343-8651

    e-ISSN:1432-0991

    IF/分区:2.6/Q3

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    Differential Microbial Composition and Fiber Degradation in Two Sloth Species (Bradypus variegatus and Choloepus hoffmanni)