Background: Recent advancements in Artificial Intelligence (AI) have transformed the healthcare field, particularly through chatbots like ChatGPT, OpenEvidence, and MediSearch. These tools analyze complex data to aid clinical decision-making, enhancing efficiency in diagnosis, treatment planning, and patient management. When applied in the "All-on-Four" dental implant concept, AI facilitates immediate prosthetic restorations and meets the demand for expert guidance. This integration boosts the long-term success of surgical outcomes by providing real-time support and improving patient education and postoperative satisfaction. This study aimed to evaluate the effectiveness of three AI-powered chatbots-ChatGPT 4.0, OpenEvidence, and MediSearch-in answering frequently asked questions regarding the All-on-Four dental implant concept.

Method: This study investigated the response accuracy of three AI-powered chatbots to common queries about the All-on-Four dental implant concept. Using alsoasked.com, twenty pertinent questions-ten patient-focused and ten technical-were identified. Oral and maxillofacial surgeons evaluated the chatbot responses using a 5-point Likert scale. Statistical analysis was performed with the Kruskal-Wallis test, supplemented by pairwise Mann-Whitney U tests with Bonferroni correction, to assess the significance of differences among the chatbots' performances.

Results: The Kruskal-Wallis test showed statistically significant differences between the three chatbots for both patient and technical questions (p < 0.01). Pairwise comparisons were evaluated using the Mann-Whitney U test. While significant differences were found among each chatbot for patient questions, no significant difference was observed between ChatGPT and MediSearch for technical questions (p = 0.158). When comparing responses of the same chatbot to patient and technical questions, it was found that MediSearch performed better in technical questions (p < 0.001).

Conclusion: Advancements in technology have made AI-powered chatbots an inevitable influence in specialized medical fields such as Oral, Maxillofacial Surgery. Our findings indicate that these chatbots can provide valuable information for patients undergoing medical procedures and serve as a resource for healthcare professionals.

Keywords: All on four; Artificial intelligence; ChatGPT; Chatbot; Dental implant; Medisearch; OpenEvidence.

© 2025. The Author(s).

背景： 近期的人工智能（AI）技术进步已经改变了医疗领域，特别是在诸如ChatGPT、OpenEvidence和MediSearch等聊天机器人的帮助下。这些工具分析复杂数据以辅助临床决策，提高诊断、治疗计划和患者管理的效率。当应用于“全口四颗种植体”概念时，人工智能能够促进即刻修复工作并满足专家指导的需求。这种集成通过提供实时支持来提升手术结果的长期成功率，并改善患者的教育及术后满意度。本研究旨在评估三个由AI驱动的聊天机器人（ChatGPT 4.0、OpenEvidence和MediSearch）在回答有关“全口四颗种植体”概念常见问题方面的有效性。

方法： 这项研究调查了三个由AI驱动的聊天机器人对关于“全口四颗种植体”概念的常见问题的回答准确性。使用alsoasked.com网站，确定了二十个相关问题——十个面向患者的问题和十个技术性问题。口腔颌面外科医生使用五级李克特量表评估聊天机器人的回复。统计分析采用Kruskal-Wallis检验，并辅以成对Mann-Whitney U检验（Bonferroni校正），以评估各聊天机器人性能差异的显著性。

结果： Kruskal-Wallis检验显示，对于面向患者和技术的问题，三个聊天机器人的表现存在统计学上的显著差异（p

结论： 技术的进步使由AI驱动的聊天机器人成为口腔颌面外科等专业医疗领域不可避免的影响。我们的研究结果表明，这些聊天机器人可以为接受医学程序的患者提供有价值的信息，并且可以作为医疗专业人员的资源。

关键词： 全口四颗种植体；人工智能；ChatGPT；聊天机器人；牙科植入物；Medisearch；OpenEvidence.