Astragaloside IV inhibits the growth of obesity-associated triple-negative breast cancer by activating FOXA1 transcription factor to regulate GAL3ST1-GalCer signaling and remodel sphingolipid metabolism
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Background: Obesity is linked to a heightened risk of developing triple-negative breast cancer (TNBC). Obesity-associated triple-negative breast cancer (OA-TNBC) presents limited therapeutic options and is characterized by a poor... ...