Pharmacological inhibition of glutamate dehydrogenase 1 (GLUD1) improves functional recovery of neuromuscular junctions and muscle function in Duchenne muscular dystrophy
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Presynaptic terminals of neuromuscular junctions (NMJs) are sensitive to glutamate, which contributes to NMJ plasticity and synaptic neurotransmission. However, the effect of glutamate on neurotransmission and its pharmacological modulation in muscle pathologi... ...