Background Infertility is the inability to conceive after a period of one year of regular unprotected intercourse. The problem of infertility has affected about 10-15% of couples worldwide including Nepal. About 6.9-9.3% is the approximate prevalence of infertility in developing countries. Objective To investigate the age distribution and ethnicity, factors of infertility, and association between age of marriage and infertility among infertile couples attending infertility clinic in the tertiary care. Method A Descriptive Cross-Sectional study was carried out among the participants (n=156) those enrolled between 1st March 2024 and 30thMay 2024 among reproductive age group couples attending in Infertility clinic of Paropakar Maternity and Women's Hospital. Data was collected and analyzed in by using SPSS version 17.0. Result Among 156 infertile couples,19% Brahman, 34% were Chhetri followed by 24% Newar, 16% Mongolian and 7% Madhesi. The study revealed that infertility in 34% of cases was female, 30.1% was male, 22.4% is both male and female, and 13.5% is unknown. The study found that out of 53 infertile females, 41.51% had tubal abnormalities, followed by ovarian, multiple, and uterine abnormalities. The most common problem studied in male was semen abnormalities like asthenozoospermia, oligozoospermia, azoospermia, and teratozoospermia. The mean age of male was 33.37 years with minimum age being 20 years and maximum 48 years. In case of female subjects, mean age was 30.56 years with youngest age being 18 and oldest being 44. Conclusion Infertility is a global health challenge as the fertility rate has been steadily falling since 1976. The incidence of secondary infertility was found to be 6.9-9.3%. This may be linked to changes in people's socioeconomic situations, such as women not having better access to healthcare and education, as well as the successful execution of government policy resource. Fertility varies, nevertheless, depending on factors including caste/ethnic group, religion, ecological zone, and residential region. We should aim to raise the nation's literacy rate and begin the improvement at the local level.

背景 不孕是指一对夫妇在一年内规律的无保护性生活后仍无法怀孕。不孕问题影响了全球约10-15%的夫妇，包括尼泊尔。发展中国家的不孕症患病率约为6.9-9.3%。目的 研究不育夫妇的年龄分布和民族构成、不孕因素以及结婚年龄与不孕之间的关联。方法 在2024年3月1日至2024年5月30日期间，对参加三级护理不孕症诊所的受试者（n=156）进行描述性横断面研究。数据通过SPSS版本17.0收集和分析。结果 在156对不育夫妇中，19%为婆罗门族裔，34%为刹帝利族裔，24%为纽瓦尔族裔，16%为蒙古利亚人，7%为马拉迪人。研究显示，在所有病例中，女性不孕占34%，男性不孕占30.1%，男女双方均有问题的占22.4%，未知原因占13.5%。在调查到的53名不育女性中，41.51%患有输卵管异常，其次是卵巢、多发性和子宫异常。研究发现，在男性中最常见的问题是精液异常，包括运动性精子减少症、少精症、无精症和形态异常精子症。男性的平均年龄为33.37岁，最小年龄为20岁，最大年龄为48岁。女性受试者的平均年龄为30.56岁，最年轻的是18岁，最年长的是44岁。结论 不孕是全球健康挑战之一，自1976年以来生育率一直在稳步下降。继发性不孕的发生率为6.9-9.3%。这可能与人们的社会经济状况变化有关，例如女性没有更好的医疗保健和教育机会，以及政府政策资源的成功执行。然而，生育能力根据包括种姓/民族、宗教、生态区域和地区居住等因素而有所不同。我们应该努力提高国家的识字率，并从地方层面开始改进。