Sirtuin-3 activation by honokiol attenuated anesthesia/surgery-induced cognitive impairment and neuronal ferroptosis via inhibiting mitochondrial GPX4 acetylation
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Background: Perioperative neurocognitive disorder (PND), a prevalent neurological complication in elderly patients following anesthesia and surgery, has recently been linked to ferroptosis as a central pathogenic mechanism. Sirtu... ...
