Species difference in the excretion routes of Ciprofol (HSK3486) in rats and humans: Contribution of hepatic transporters and renal UDP-glucuronosyltransferase enzymes
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The primary metabolic pathways of the anesthetic Ciprofol in both humans and rats are glucuronidation (M4) and 4-hydroxylation, followed by glucuronidation (M5-1). However, there are significant interspecies differences in their excretion routes. M4 and M5-1 a... ...
