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Bilateral sino-nasal-orbital fungal necrosis associated with hemophagocytic lymphohistiocytosis

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Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory condition caused by hyperactive T cells and macrophages, which release pro-inflammatory cytokines. The diagnosis is based on eight criteria: fever, bi- or tri-lineage cytopenias, splenomegaly... ...