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Hypercoagulability and the A1298C MTHFR Mutation: Case Series of Unexplained Pulmonary Embolism

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Methylenetetrahydrofolate reductase gene (MTHFR) mutations can lead to hyperhomocysteinemia, a known risk factor for venous thromboembolism. In some studies, the A1298C and C677T polymorphisms of the MTHFR gene have been linked to thrombosis, though their clin... ...