Discovery of Carbazole and Theophylline-Based Amyloid Inhibitor for the Promotion of Neuroprotection
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The amyloid-beta 42 (Aβ42) peptide assembles into neurotoxic soluble oligomers and extracellular fibrillary aggregates during the progression of Alzheimer's disease (AD), which ultimately leads to amyloid plaque in the brain, causing major disruption of the ... ...