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Case Reports Infectious disorders drug targets. 2025 May 26. doi: 10.2174/0118715265371254250519044856 0.02024

Tuberculous Broncho-Esophageal Fistula in an Adult Male: A Rare Case Managed Conservatively

一例罕见的成人男性结核性支气管食管瘘保守治疗病例报告 翻译改进

Jitendra Singh  1  2, Nilesh Kumar  2, Abhishek Borkotoky  2, Kailash Kumar  2, Sarvesh Verma  2, Anju Dinkar  3  4, Dawesh Prakash Yadav  5

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作者单位

  • 1 Department of General Medicine, King George`s Medical University, Lucknow, Uttar Pradesh, India.
  • 2 Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
  • 3 Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
  • 4 Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
  • 5 Department of Gastroenterology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
  • DOI: 10.2174/0118715265371254250519044856 PMID: 40442902

    摘要 中英对照阅读

    Introduction: Tuberculosis (TB) is a widespread infectious disease caused by Mycobacterium tuberculosis. It predominantly affects the lungs but can involve any organ in the body. Tracheo-oesophageal fistula (TEF) is one of the rare extrapulmonary manifestations of TB.

    Case report: A 27-year-old male, otherwise healthy, reported to our outpatient department with complaints of fever, persistent cough, and significant weight loss. Subsequently, he was diagnosed with tuberculous tracheo-oesophageal fistula and pulmonary tuberculosis.

    Discussion: The patient had an elevated ESR (52 mm) and underwent multiple imaging studies, including two normal barium swallow tests. Upper gastrointestinal endoscopy (UGIE) revealed two esophageal ulcers, one with a fistulous tract. Biopsy results suggested chronic esophagitis with granulomatous inflammation. Contrast-enhanced CT (CECT) of the thorax showed esophageal irregularities, air foci, and contrast extravasation into the bronchi, along with mediastinal lymphadenopathy and centrilobular nodules. Clinical and investigative findings suggested pulmonary tuberculosis with a tracheoesophageal fistula. The patient was discharged on a six-month antitubercular regimen with nutritional support via a nasogastric tube. Stent installation was planned if follow-up results were unfavorable.

    Conclusion: Although tuberculosis is highly prevalent in India, TEF of tuberculous origin has been infrequently documented, particularly in young, healthy, immunocompetent individuals. The patient was successfully cured after initiating antitubercular therapy and subsequent follow-up.

    Keywords: Bronchoesophageal; atypical presentation; cold abscess; diabetes mellitus.; pulmonary tuberculosis; tuberculosis.

    Keywords:conservative management; rare case

    简介: 结核病(TB)是由结核分枝杆菌引起的一种广泛传播的传染病,主要影响肺部,但也可以涉及身体任何器官。气管食管瘘(TEF)是结核病罕见的肺外表现之一。

    病例报告: 一名27岁的男性患者,身体健康,因发热、持续咳嗽和明显体重下降等症状前来我院门诊就诊。随后被诊断为结核性气管食管瘘和肺结核。

    讨论: 患者的红细胞沉降率(ESR)升高至52毫米,并进行了多次影像学检查,包括两次正常的钡餐试验。上消化道内镜显示两个食管溃疡,其中一个有瘘管形成。活检结果显示为慢性食管炎伴肉芽肿性炎症。胸部增强CT扫描显示食管不规则、气泡和对比剂外溢至支气管,并伴有纵隔淋巴结增大及中心肺小结节。临床和检查结果提示存在肺结核并发气管食管瘘。患者出院时开始接受为期六个月的抗结核治疗并辅以鼻胃管营养支持,若后续随访结果不佳则计划安装支架。

    结论: 尽管印度地区结核病高发,但由结核引起的TEF在年轻、健康且免疫功能正常的个体中罕见。患者在接受抗结核治疗及后续随访后得到了成功治愈。

    关键词:气管食管瘘;非典型表现;冷脓肿;糖尿病 mellitus;肺结核;结核病。

    Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

    关键词:结核性支气管食管瘘; 保守治疗; 罕见病例

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    期刊名:Infectious disorders - drug targets

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    ISSN:1871-5265

    e-ISSN:2212-3989

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    Tuberculous Broncho-Esophageal Fistula in an Adult Male: A Rare Case Managed Conservatively