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Wolcott-Rallison Syndrome - crosstalk between PERK- EIF2A and type II interferon signaling

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Immune activation is not reported in children with Wolcott-Rallison syndrome (WRS). We observed a pattern of immune activation pre-transplant in three children with WRS that was consistent with increased interferon-γ (IFN-γ) and its regulated chemokine, CXCL... ...