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Randomized Controlled Trial Techniques in coloproctology. 2025 May 27;29(1):125. doi: 10.1007/s10151-025-03145-z Q32.72024

Outcomes of laparoscopic ventral mesh rectopexy versus trans-vaginal repair in management of anterior rectocele, a randomized controlled trial

经腹腔镜网片直肠固定术与经阴道修补术治疗前壁直肠膨出的疗效比较:一项随机对照试验 翻译改进

A Sanad  1, A Sakr  2  3, H Elfeki  1, W Omar  1, W Thabet  1, E Fouda  1, E Abdallah  1, S A Elbaz  1

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作者单位

  • 1 Colorectal Surgery Unit, Department of Surgery, Mansoura University Hospitals, Mansoura, Egypt.
  • 2 Colorectal Surgery Unit, Department of Surgery, Mansoura University Hospitals, Mansoura, Egypt. Ahmadsakr1987@gmail.com.
  • 3 Department of General Surgery, King Khalid University, Abha, Saudi Arabia. Ahmadsakr1987@gmail.com.
  • DOI: 10.1007/s10151-025-03145-z PMID: 40423835

    摘要 中英对照阅读

    Background: Anterior rectocele is one of the most common colorectal problems with symptoms of obstructed defecation or rectal emptying difficulties. The aim of this study is to compare the outcomes of laparoscopic ventral mesh rectopexy (LVMR) and transvaginal repair (TVR) for symptomatic anterior rectocele.

    Methods: This is a prospective randomized controlled trial conducted with 40 women. Patients were randomized into two groups. LVMR was done in the first group, whereas the second group underwent TVR. Patient outcomes were compared regarding improvement in constipation using the Cleveland Clinic Constipation (CCC) score and sexual-related quality of life score using the short form of the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) at 6- and 12-month follow-up.

    Results: Forty females were enrolled in this trial. Each group comprised 20 patients. Preoperatively, the CCC score was 17 ± 2.8 in the LVMR group vs. 17.3 ± 2 in the TVR group (P = 0.278). A significant decrease in the constipation score was recorded in each group at 6 and 12 months after surgery. Regarding sexual function, the mean PISQ-12 score at 6 months was 32 ± 3.9 for LVMR vs. 35 ± 1.4 for TVR, P < 0.001), while at 12 months no difference was noted between the two groups. However, each group showed significant improvement in the PISQ-12 score at 6- and 12-month follow-up.

    Conclusion: Comparable results were noted for LVMR and TVR in management of anterior rectocele. Obstructive defecation symptoms and sexual function showed significant improvement after 1 year of follow-up. Nevertheless, long-term follow-up is needed.

    Clinical trial registration: The study was registered in the clinical trials registry with registration number NCT06633172.

    Keywords: Constipation; Functional outcome; Rectocele; Transvaginal repair; Ventral mesh rectopexy.

    Keywords:anterior rectocele; randomized controlled trial

    背景: 前壁直肠膨出是常见的结直肠问题之一,症状包括排便障碍或直肠清空困难。本研究的目的是比较腹腔镜前侧网片直肠悬吊术(LVMR)和经阴道修补术(TVR)治疗有症状的前壁直肠膨出的效果。

    方法: 这是一项针对40名女性进行的前瞻性随机对照试验。患者被随机分为两组,第一组接受LVMR手术,而第二组则接受TVR手术。在术后6个月和12个月的随访中,通过克利夫兰诊所便秘(CCC)评分以及使用盆腔器官脱垂/尿失禁性功能简表(PISQ-12)评估两组患者便秘症状改善情况及与性生活相关的生活质量评分。

    结果: 本试验共纳入40名女性,每组各20例。术前LVMR组的CCC评分为17 ± 2.8,TVR组为17.3 ± 2(P = 0.278)。术后6个月和12个月时,两组便秘评分均显著下降。关于性功能方面,LVMR组在6个月时的平均PISQ-12评分为32 ± 3.9,而TVR组为35 ± 1.4(P

    结论: 对于前壁直肠膨出的治疗,LVMR和TVR具有类似的效果。排便障碍症状及性功能在为期一年的随访中均有明显改善。然而,仍需进行长期随访观察。

    临床试验注册: 该研究已在临床试验登记处注册,注册号为NCT06633172

    关键词: 便秘;功能结局;直肠膨出;经阴道修补术;前侧网片直肠悬吊术。

    关键词:前壁rectocele; 随机对照试验

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    期刊名:Techniques in coloproctology

    缩写:TECH COLOPROCTOL

    ISSN:1123-6337

    e-ISSN:1128-045X

    IF/分区:2.7/Q3

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    Outcomes of laparoscopic ventral mesh rectopexy versus trans-vaginal repair in management of anterior rectocele, a randomized controlled trial