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Spermine Enhances Cholesterol Effluence of Macrophages Through Caspase 2-Mediated Autophagy

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Background: Spermine (SPM) is known to play a role in regulating cholesterol efflux of macrophages, which is a critical anti-atherosclerotic pathway, but the underlying mechanism remains elusive. The deficiency of caspase 2 (CASP... ...