Hb Lepore Rochester-MN, a novel βδβ double crossover hemoglobin variant
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Introduction: The β-globin gene cluster harbors highly homologous globin genes. Crossover events involving the δ (HBD) and β (HBB) genes result in Lepore (δβ) and anti-Lepore (βδ) hemoglobins (Hbs). Recently, double crosso... ...