RNAi targeting heparin cofactor II promotes hemostasis in a canine model of acquired hemophilia A
{{output}}
Heparin cofactor II (HCII) is a critical anticoagulant protein that inactivates thrombin. In our previous mouse studies, we demonstrated that GalNAc-HCII, a small interfering RNA (siRNA) targeting HCII conjugated with N-acetylgalactosamine (GalNAc), exhibited ... ...
