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Enhancing menaquinone-7 biosynthesis by optimized fermentation strategies and fed-batch cultivation of food-derived Bacillus subtilis

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Background: Menaquinone-7 (MK-7), a type of vitamin K2 (VK2), is considered to be a health-promoting functional ingredient in the current recommended dietary supply. However, it is a challenge to isolate high-yield MK-7-producing... ...