Characterization of ene reaction products of Cookson-type fluorescent reagents and their application for recognizing amyloid β aggregation
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The Cookson reagent (4-phenyl-1,2,4-triazoline-3,5-dione, PTAD) is a powerful dienophile for the Diels-Alder reaction and is used as a protecting group for conjugated dienes in organic chemistry. PTAD also undergoes a selective ene reaction with tyrosine (Tyr)... ...
