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Dominant Negative PTEN Alterations in Endometrial Carcinoma Are Associated With Retained Immunohistochemical PTEN Expression

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PTEN immunohistochemistry (IHC) is considered complimentary for assessment of PTEN abnormality in endometrial carcinoma (EC), since PTEN IHC staining pattern does not entirely correlate with the presence and absence of mutations on sequencing. A set of functio... ...