首页 正文

Tumor ploidy determination in low-pass whole genome sequencing and allelic copy number visualization using the Constellation Plot

{{output}}
Ploidy determination across the genome has been challenging for low-pass-WGS tumor-only samples. We present BACDAC, a method that calculates tumor ploidy down to 1.2X effective tumor coverage. Allele fraction patterns displayed in the Constellation Plot verify... ...