Elevated Bromide Levels due to Tazemetostat Therapy Treated With Salt and Water Supplementation in Two Children With Atypical Teratoid Rhabdoid Tumor
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Atypical teratoid rhabdoid tumor (ATRT) is an embryonal CNS tumor that afflicts young children. The molecular process associated with ATRT is loss of SMARCB1 or SMARCA4, which causes EZH2 overactivation. Tazemetostat hydrobromide is an EZH2 inhibitor, which ha... ...
