This study examines the neural underpinnings of the intention to use cognitive training digital therapeutics among older adults with subjective memory complaints. A total of 23 older adults with a clinical dementia rating score of 0.5-commonly interpreted as indicative of very mild cognitive impairment-participated in cognitive training using a smartphone application. Leveraging functional near-infrared spectroscopy during cognitive training and the technology acceptance model, this research investigates the predictive role of neural activation on the intention to use. Results revealed that higher activation in the right medial prefrontal cortex and reduced activation in the right dorsolateral prefrontal cortex during cognitive training were significantly associated with increased intention to use. The interplay between neural mechanisms in the motivational system and the cognitive control system at the prefrontal cortex level plays a critical role in shaping the intention to use.

Keywords: cognitive training; fNIRS; neural predictors; older adults; technology acceptance model.

这项研究探讨了老年人主观记忆抱怨者使用认知训练数字疗法的意图背后的神经机制。共有23名临床痴呆评定得分为0.5（通常解释为轻度认知障碍）的老年人参与了智能手机应用程序的认知训练。通过在进行认知训练期间利用功能性近红外光谱成像技术，并结合技术接受模型，本研究探讨了神经激活对使用意图预测作用。结果表明，在认知训练过程中右内侧前额皮层的较高激活和右背外侧前额皮层的较低激活与更高的使用意图显著相关。动机系统和认知控制系统在前额叶水平上的相互作用在塑造使用意图方面起着关键作用。

关键词： 认知训练；fNIRS；神经预测因子；老年人；技术接受模型。