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The synergistic effect of imipenem combined with ceftazidime-avibactam against Klebsiella pneumoniae with alternating resistance to CZA and carbapenem

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Purposes: The purpose of this study was to explore the mechanisms of resistance of clinically isolated K. pneumoniae, which is alternately resistant to carbapenems and ceftazidime/avibactam (CZA), and therapeutic strategies. ... ...