Urologia internationalis. 2025 May 17:1-14. doi: 10.1159/000546458 Q31.32025
Efficacy and Safety of a Novel <5mm Ureteral Dilation Balloon Catheter in Holmium Laser Surgery for Ureteral Calculi with Physiological Narrowing: A Randomized Controlled Trial
一种新型疗法的效果和安全性 翻译改进
He Zhang, Lin Zhang, Yuhan Hou, Xiangmin Zhang, Yiyang Liu, Zhihui Dong, Jian Chu, Jianwei Cao
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DOI: 10.1159/000546458 PMID: 40383121
摘要 中英对照阅读
背景： “难治性输尿管”特指狭窄且迂曲的输尿管，通常需要分期手术治疗。我们首次提出了结合可视输尿管扩张气球导管与钬激光碎石术，用于治疗输尿管狭窄患者的输尿管结石。
方法： 一项前瞻性、多中心、随机、开放标签对照研究于2021年7月至2023年7月期间招募了60名患有输尿管狭窄的输尿管结石患者。患者被随机分配到第一阶段输尿管镜碎石术结合直接可视化气球扩张（DVBD+FUS）或使用内芯进行扩张（DUS+S）。主要结局指标为首次手术中鞘置入的成功率，通过二次手术率评估。次要结局指标包括结石清除率、术后血清肌酐升高、术后贫血发生率、总住院时间、手术时间、输尿管支架移除时间、输尿管损伤和总手术费用。
结果： 共纳入了60名年龄在24至68岁之间的患者，结石直径范围为0.6至2厘米（平均1.4厘米）。第一阶段手术后，DUS+S组中有17例（56.67%）和DVBD+FUS组中4例（13.3%）需要二次手术（P
结论： 我们的研究表明，DVBD+FUS可以作为治疗输尿管狭窄患者输尿管结石的有效且安全的策略。此外，总住院时间、手术时间和费用在采用DVBD+FUS治疗后显著降低。
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Efficacy and Safety of a Novel <5mm Ureteral Dilation Balloon Catheter in Holmium Laser Surgery for Ureteral Calculi with Physiological Narrowing: A Randomized Controlled Trial