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Direct oral anticoagulants versus vitamin-K antagonists in patients with single or double-positive antiphospholipid syndrome: a systematic review and meta-analysis

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Introduction: Antiphospholipid syndrome (APS) is a heterogeneous disease where the presence of antiphospholipid antibodies (aPL) results in blood clot formation. Compared to those with a triple-positive antibody profile, the opti... ...