Activation of Mechanosensitive Ion Channels Induces Autocrine and Paracrine Networks in Craniocervical Squamous Cell Carcinoma Cell via Endothelin Signaling
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Endothelin (ET) is a peptide comprising 21 amino acids, and its G-protein coupled ETA and ETB receptors are expressed in both cancer cells and cancer-associated cells. Cancer cells excessively express ETA and ETB receptors, and mechanical stimulation promotes ... ...