Solid Supersaturated Self-Nanoemulsifying Drug Delivery System for Abiraterone Acetate: Improved Drug loading, Dissolution, Cellular Uptake and Anticancer Activity
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Abiraterone acetate (ABT) is an androgen biosynthesis inhibitor approved for the treatment of prostate cancer. However, the treatment course of ABT is constrained by its high dose, poor solubility and permeability issues. A solid supersaturated self-nanoemulsi... ...