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The role of hepatic sinusoidal microenvironment in NASH: pathogenesis, animal models, and therapeutic prospects

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The incidence of nonalcoholic steatohepatitis (NASH) is increasing annually, posing a significant threat to human health. NASH is typified by hepatic steatosis, inflammation, and hepatocellular injury, frequently culminating in fibrosis and cirrhosis. Yet, the... ...