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Non-Antigen-Specific B Cells Induced Regulatory CD4+ T Cells Through Decreasing T Cell Activation

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Our previous findings demonstrated that naïve B cells elicit suppressive CD4+ regulatory T (Treg) cells, named as Treg-of-B cells. However, the capability of antigen-specific B cells in that process remains unclear. Using ovalbumin (OVA) as a model antigen, t... ...