Coproporphyrin I as an in vitro fluorescent probe to measure OATP1B1 transport activity
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The organic anion transporting polypeptide 1B1 (OATP1B1) is a major pharmacologically relevant hepatic uptake transporter that mediates the clearance of many drugs. The OATP1B1 substrate coproporphyrin I (CPI) has been continually shown to be a reliable and sp... ...