The increasing interest in protein and peptide coacervates is accompanied by the development of various applications, from drug delivery to biosensor preparation. However, the impact of peptide end groups and charges on coacervation remains unclear. For this purpose, we designed four peptide derivatives with varying end groups and net charges. These inherently fluorescent peptides readily formed coacervates in solution or during evaporation. The ability to control the coacervation process, the coacervate's appearance, and the encapsulation capabilities were thoroughly investigated. The coacervates displayed significant antioxidant properties, protecting the encapsulated material. Additionally, control of the deposition of coacervates on surfaces was achieved. These abilities highlight the potential of these coacervates in biotechnological applications, including biosensor development and the delivery of compounds such as drugs and dietary supplements. Exploiting the dynamic characteristics of coacervates with the unique properties of these peptides underscores their practical advantages.

Keywords: antioxidant; concentration gradient; controlled deposition; dietary supplements; peptide coacervates.

对蛋白质和肽共聚物日益增长的兴趣伴随着各种应用的发展，从药物递送到生物传感器制备。然而，肽末端基团和电荷对共聚化的影响仍然不清楚。为此，我们设计了四种具有不同末端基团和净电荷的肽衍生物。这些固有的荧光肽在溶液中或蒸发过程中易于形成共聚物。我们彻底研究了控制共聚化过程、共聚物外观以及封装能力的能力。共聚物表现出显著的抗氧化性能，可以保护封装材料。此外，还实现了对共聚物在表面沉积的控制。这些能力突显了这些共聚物在生物技术应用中的潜力，包括生物传感器开发和药物等化合物的递送。利用共聚物的动力学特性及其独特的肽性质强调了它们的实际优势。

关键词：抗氧化；浓度梯度；可控沉积；膳食补充剂；肽共聚物。