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Targeting Calprotectin S100A8/A9 to Overcome AML Progression in DNMT3A-Mutant Cells

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Objective: To investigate the effects of calprotectin (S100A8/A9) on the biological activity of acute myeloid leukemia (AML) cells harboring a DNA methyltransferase 3A (DNMT3A) mutation and to explore the underlying molecular mec... ...