Abnormal nucleoli architecture and aggregate formation in Nucleophosmin mutated Acute Myeloid Leukaemia
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Mutations in the Nucleophosmin (NPM1) gene represent the most common genetic alteration in Acute Myeloid Leukaemia (AML) and result in mis-localisation of the mutated protein from a predominantly nucleolar localisation to a predominantly cytoplasmic distributi... ...
