Design, synthesis, and mechanism study of novel natural-based isoquinolone derivatives as potential antifungal agents
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A series of isoquinolone compounds Ia-Iq containing amide moiety were rationally designed and synthesized based-on isoquinolone alkaloids. Their structures were confirmed by 1H NMR,13C NMR and HRMS. Most of the title compounds showed medium to excellent antifu... ...
