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Case Report: Myeloid neoplasms with the t(3;12)(q26.2;p13.1)/ MECOM-ETV6 translocation: report of two new cases and review of the literature

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The MECOM (MDS1 and EVI1 complex locus) gene, located at 3q26.2, encodes an oncogenic transcription factor implicated in multiple signaling pathways. Rearrangements involving MECOM/3q26.2, including inversions, translocations, insertions and cryptic chromosoma... ...