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Valproic acid promotes transcriptional activation of Drd2 by mediating histone acetylation to inhibit the mTOR-Pttg1 signaling axis and exerts anti-PitNETs activity

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Background: Valproic acid (VPA), a short branched-chain fatty acid derived from valeric acid naturally produced by Valeriana officinalis L., is widely used in clinical settings for the treatment of epilepsy. Furthermore, VPA has ... ...