Introduction: Metabolic Syndrome (MetS) is a global health concern characterised by cardiometabolic risk factors, dysregulated adipokine signalling and inflammation. The study aimed to assess the serum levels of omentin and visfatin in patients with metabolic syndrome.

Methods: The 84-subject hospital-based case-control study included 18-55 years, both genders. Anthropometry, medical history, fasting plasma glucose (FPG), lipid profile, and HOMA-IR were collected. Insulin, omentin, and visfatin were measured using ELISA.

Results: Omentin and visfatin levels significantly differed between groups (p < 0.05). The median omentin levels were 50.74 and 45.25; visfatin levels were 0.064 and 0.001, respectively. Omentin correlated with waist circumference, blood pressure, and FPG in controls, while visfatin correlated with HDL and BMI among cases (p < 0.05). Omentin and visfatin were elevated in cases. However, no significant correlation between omentin and visfatin with lipid parameters could be established.

Conclusion: Omentin and visfatin levels varied significantly between metabolic syndrome and controls; their correlation with MetS criteria was not significant.

Keywords: Adipokines; body mass index; insulin resistance; obesity.

简介： 代谢综合征（MetS）是一种全球性的健康问题，其特征为心血管代谢风险因素、脂肪细胞因子信号失调和炎症。本研究旨在评估代谢综合征患者血清中omentin和visfatin的水平。

方法： 这项基于医院的病例对照研究包括了84名年龄在18-55岁之间的受试者，男女均有。收集了体质测量数据、病史、空腹血糖（FPG）、血脂谱和HOMA-IR等信息。使用ELISA法测定胰岛素、omentin和visfatin的水平。

结果： 组间omentin和visfatin水平有显著差异（p

结论： 代谢综合征患者和对照组的omentin及visfatin水平有显著差异；但这些因子与MetS标准之间的相关性并不显著。

关键词： 脂肪细胞因子；体质指数；胰岛素抵抗；肥胖。