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The bridge-like lipid transport protein VPS13C/PARK23 mediates ER-lysosome contacts following lysosome damage

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Based on genetic studies, lysosome dysfunction is thought to play a pathogenetic role in Parkinson's disease. Here we show that VPS13C, a bridge-like lipid-transport protein and a Parkinson's disease gene, is a sensor of lysosome stress or damage. Following ... ...