Design, Fabrication, and In Vitro - In Vivo Evaluation of Surface-Engineered Pyrazinamide-Loaded Lipid Nanoparticles for Tuberculosis Therapy
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Pyrazinamide (PYZ), a nicotinamide derivative, is an essential first-line anti-TB drug. However, its dose-dependent hepatotoxicity poses a considerable challenge, accentuating the need for improved delivery approaches. The key objective of the research work wa... ...