Saikosaponin D, a triterpene saponin from Bupleurum falcatum, restores circadian rhythm and attenuates hepatic fibrosis via Esr1-Per2 axis
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Hepatic fibrosis, a precursor to chronic liver diseases, is linked to circadian rhythm disruptions. This study investigates the anti-fibrotic effects of saikosaponin D (SSd) from Bupleurum falcatum L. and its regulation of circadian genes. Transcriptomic and s... ...
